Polyclonal antiserum, also called polyclonal antibody, is the immune serum obtained by immunizing animals with Antigen. Antigen molecules stimulate the immune system, induce a number of B cell clones to be activated, produce neutralizing antibodies and release them into the serum to provide immune protection. This kind of serum containing immunoglobulins that can bind to a variety of antigen epitopes is called Polyclonal serum.
It is suitable for the production of antiserum against different diseases by using different bacteria, viruses and toxins.
Description: Horse serums containing specific antitoxins and antibodies.
Feature: Mars Bio has over 20 years of professional experience in providing high-quality serums to pharmaceutical companies. The end products continue to
dominate the local Chinese market and are sold to over 30 countries worldwide.
Applications: The production of antitoxins and specific antibodies, cell culture media.
Description: Serum containing pregnant mare serum gonadotropin (PMSG)
Feature: Due to our individualized herd management andwith advanced purification and lyophizing technology, we can supply different activity lyophilized powder (500IU/mg 1000IU/mg 2000IU/mg 5000IU/mg or according to the customer's requirement).
Applications: For production of PMSG intermediate and various final products.
Description: A gonadotropin hormone produced in the chorion of pregnant mares, also referred to as equine chorionic gonadotropin (eCG).
Applications: PMSG is commonly used to induce ovulation in livestock prior to artificial insemination. It is also frequently used in the treatment of ovarian agenesis and impaired spermatogenesis. The product is typically sold in the form of lyophilized powder.
Product characteristics: an animal oil, horse fat as the main extraction raw material; the main components are oleic acid, linoleic acid and palmitic acid; rich in nutrients (vitamin E and linolenic acid), of which alpha linolenic acid, has the effect of promoting lipolysis in vivo; rich in unsaturated fatty acids, with good permeability
Scope of application: Active ingredient with natural antioxidant properties, is a good natural antioxidant, which is expected to be applied to health products, pharmaceuticals, cosmetics and other industries; contains high content of linoleic acid, using horse oil to treat atopic dermatitis; polyunsaturated fatty acid, has a good repair effect on skin barrier function.Nursing for sensitive muscles is better than many vegetable oils.
Description: Placenta excreted by mare when foals are born.
Feature: Placenta plays an important role in building embryos as it comprises almost all the nutrients needed for life - proteins, lipids, carbohydrates, nucleic acids, vitamins, and minerals. It is therefore a best natural ingredient for health and beauty improvement.
(1) Skincare: Horse placenta is a rich source of amino acids that is vital in producing renewed skin. It activates the production of collagen, elastin, & hyaluronic acid needed by the skin to replace old cells with new ones. During this cell regeneration, impaired and aged skin is naturally reborn to reveal a whiter, glowing, and youthful-looking skin. In Japan, it is regarded as one of the best cosmetic ingredients because of its triple action formula: whitening, anti-aging, & skin cell renewal.
(2) Health supplements: Horse placenta is used in medicines and dietary supplements to improve a wide range of health conditions including fatigue, anemia, inflammations, and disorders in blood pressure and menstruation.
Description: Horsehair fabrics are sought for their luster, durability and care properties. It has many different appearances and various purposes, including
upholstery, brushes, musical instruments, fishing lines and crafts.
Applications: Horsehair is used in upholstery (horsehair hitching, horsehair braiding etc.), bows of musical instruments, and fishing lines. It is also used in
making jewelry items such as bracelets and necklaces. Brushes made from horsehair are also used in making brushes for high-end equipment without damaging its surface.
Description: After compost, horse manure is a good source of nutrients andcontains plenty of fiber, making it an excellent soil conditioner in organic and sustainable soil management.
Applications: Horse manure is used for natural organic fertilizer. It is also frequently used in the cultivation of edible fungi due to its loose structure.
Basic information of pepsin (porcine stomach mucose)
Pepsin is a digestive protease secreted by the main cells of gastric mucosa in the stomach. Its function is to decompose the protein in food into small peptide fragments. The main cell secretes Pepsinogen, which is stimulated by gastric acid or pepsin to form pepsin. Pepsin is not directly generated by cells. Reagent scientific Grade pepsin activity : 1:150000NF 1:10000NF 1:18000BP 1:12000BP 2.3U/mg EP 1.5U/mg EP
Pepsin : mechanism of action
Pepsin should be kept in a low temperature environment (from - 20 ℃ to - 80 ℃) to prevent its self degradation. When the pH value of pepsin returned to 6, the activity of pepsin could be restored.
The digestion in the stomach is mainly for the initial decomposition of protein. Pepsin has the function of decomposing protein, but the pepsin secreted from the main cell exists as inactive pepsinogen, which must be activated and provided with the action environment similar to the gastric acid. Therefore, hydrochloric acid activates the pepsinogen and provides the acid environment for the pepsin action, which is its digestive function. The pepsinogen is mainly secreted from the stomach bottom Under the condition of ph1.5-5.0, activated to pepsin, and then decomposed to peptone, and part of protein was decomposed to tyrosine, phenylalanine and other amino acids.
Pepsin activation process
Pepsin was first expressed as zymogen, namely pepsinogen. Pepsinogen is the inactive precursor of pepsin. Its primary structure is 44 amino acids more than pepsin. In the stomach, the main cells of gastric mucosa release pepsinogen. This enzyme is activated when it encounters hydrochloric acid in gastric acid (released by gastric parietal cells). When the stomach digests food, it activates the release of pepsinogen and hydrochloric acid from the stomach wall under the action of a hormone called gastrin and vagus nerve. In the acid environment created by hydrochloric acid, pepsinogen is unfolded, so that it can shear itself in autocatalytic way, thus producing active pepsin. Then, the pepsin produced continued to cut the pepsinogen, and 44 amino acid residues were removed to produce more pepsin. This mechanism can keep the form of zymogen when there is no food digestion, which can avoid excessive pepsin digesting the gastric wall itself. It is a protective mechanism.